Early detection of risk for psychosis: overview of screening tools for the general population

Poster B110, Tuesday, October 9, 11:30 am - 1:00 pm, Essex Ballroom

Lorenzo Del Fabro1, Anna Castelnovo2, Davide Maestri1, Orsola Gambini1, Armando D'Agostino1, Alberto Parabiaghi3; 1University of Milan, Milan, Italy, 2Civic Hospital of Lugano, Lugano, Switzerland, 3Mario Negri Institute for Pharmacological Research, Milan, Italy

Early detection and treatment of psychotic symptoms might be relevant to prevent long-term, disabling outcomes of psychotic disorders. Implementation of screening tools improves possibilities of intervention in the prodromal clinical stages of psychotic disorders and plays a crucial role in the strategy of prevention in mental health. Several validated brief questionnaires can be adopted as screening tools for further diagnostic interviews in the help-seeking population; nonetheless, the role of screening instruments for the general population is still in its infancy. The aim of this review was to identify screening instruments for clinical high risk (CHR) of psychosis eligible for wide population comparing questionnaires validated for detection of risk of psychosis. A literature search was conducted to assess the diagnostic performance of different screening tools. Among 14 screening instruments selected, 5 self-report questionnaires validated for the general, non help-seeking population were identified. Sensibility and specificity of YPARQ-B, PROD-screen, BQSPS, CAPE-42 and APSS were summarized and test-characteristics of these tools were described. In conclusion, considering the highest levels of accuracy and sensitivity, the most suitable instruments for screening CHR in the general population were identified and described. Future studies are needed to assess whether the widespread use of such tools in young, non-help-seeking individuals can significantly advance early detection strategies.

Topic Area: Ultra High Risk / Prodromal Research

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