Poster A70, Monday, October 8, 11:30 am - 1:00 pm, Essex Ballroom

Olga Puig1,2, Francina Badia1, Baeza Inmaculada1,2,3, Gallegos Yuliana4, Sugranyes Gisela1,2,3, Varela Eva1, Forner Mireia1, Garcia-Rizo Clemente2,3,5, Martínez-Aran Anabel2,3,5, Granholm Eric4,6; 1Department of Child and Adolescent Psychiatry and Psychology, Institute of Neuroscience, Hospital Clínic of Barcelona, 2017SGR881, Barcelona, Catalonia., 2Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Spain., 3CERCA-IDIBAPS, Barcelona, Catalonia, Spain., 4VA San Diego Healthcare System (VASDHS), San Diego, CA 92161, USA., 5Department of Psychiatry and Psychology, Institute of Neuroscience, Hospital Clínic of Barcelona., 6Department of Psychiatry, University of California, San Diego, CA, USA.

Defeatist performance beliefs (DPB) are linked to negative symptoms and functional outcome in schizophrenia (Campellone et al., 2016). Adolescents with early-onset psychosis (Adol_EOP) have more persistent negative symptoms (Puig et al., 2017). Objectives: (1) to examine DPB in Adol_EOP, (2) to study the relationships between DPB, symptoms and functioning. METHODS: 20 Adol_EOP (14♀, age=16.00±1.84) and 14 healthy controls (12♀, age=15.71±1.48), participants in a trial about CBSST in Hospital Clínic of Barcelona (baseline data). Inclusion criteria: EOP diagnosed between 9-18 years-old (schizophrenia, schizoaffective disorder, psychosis nos); within the 5 first years after disease onset; clinical stability. Exclusion criteria: IQ<70; substance dependence disorder; neurological disorders. Instruments: PANSS, Calgary Depression Scale (CDS), Children’s Global Assessment Scale, Life Skills Profile - Adolescent version (Puig et al., 2013). DPB was extracted from the Dysfunctional Attitudes Scale - Spanish version (Sanz et al., 1993). RESULTS: EOP and control groups were homogeneous in age (t=-0.49, p=0.634) and sex (X2=1.130, p=0.288). Socioeconomic status was lower in EOP (X2=13.34, p=0.010). EOP subjects had a predominance of negative symptoms (positive symptoms=13.95±3.94; negative symptoms=17.79±3.26). Mean score of CDS was low (4.95±5.52). EOP group had lower scores in all functional measures (t>6.78, p<0.001). EOP group had more DPB than controls (43.30±16.52 vs 30.86±13.36, t=2.33, p=0.026) and it was correlated with poorer life skills (r=0.53, p=0.023) but not with symptoms. DISCUSSION: Adol_EOP had higher levels of DPB. It was correlated with poorer psychosocial functioning but not with negative symptoms. DPB might have a different role in relation with symptoms in Adol_EOP. Acknowledgments: FAK.

Topic Area: First Episode Psychosis

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