Clinical High Risk of Psychosis in Low- and Middle-income Countries: Current Status and Future Challenges.

Poster C55, Wednesday, October 10, 11:30 am - 1:00 pm, Essex Ballroom

Yasin Ibrahim1, Cheryl Corcoran2, Amelia M. Abbott-Frey2; 1Icahn School of Medicine at Mount Sinai/Elmhurst, 2Icahn School of Medicine at Mount Sinai.

Background: There are few published studies on clinical high risk status of psychosis (CHR) in low- and middle-income countries (LMIC). Here, we aim to review and synthesize the data from these published studies. Methods: A literature review was conducted using keyword searches on PubMed, Embase (Ovid), PsycINFO, Web of Science, and published posters in the International Conference on Early intervention in Mental Health, in addition to personal contacts. The inclusion criteria mandated studies provide data on the clinical high risk population. In turn, the primary outcome was the current available intervention services for CHR while secondary outcomes were the epidemiology, phenomenology, and biologic markers of the CHR subjects in LMICs. Results: In total, 53 studies were identified, which focused on intervention (8), epidemiology (13), phenomenology (19), and biological markers (13) in CHR. The main findings of these studies are summarized in this review. Conclusion: Contrary to the high-income countries (HIC), the vast majority of LMIC are significantly lagging behind in the field of research on CHR status and only a few countries were able to achieve some academic and clinical progress. Academic institutions in HICs are urged to build partnerships with mirroring institutions in LMICs to help close that gap.

Topic Area: Psychosocial Interventions

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