Family Adaptability and Cohesion Evaluation in Youth At-Risk for Serious Mental Illness: Results from the PROCAN Study
Poster B81, Tuesday, October%209, 11:30%20am%20-%201:00%20pm, Essex%20Ballroom
Olga Santesteban-Echarri1, Glenda MacQueen1, Benjamin I. Goldstein2,3, Jian L. Wang4,5, Sidney H. Kennedy6,7,8,9,10, Signe Bray1,11,12, Catherine Lebel1,11,12, Jean Addington1; 1Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Calgary, Alberta Canada, 2Centre for Youth Bipolar Disorder, Sunnybrook Health Sciences Centre, Toronto, Ontario Canada, 3Departments of Psychiatry and Pharmacology, Faculty of Medicine, University of Toronto, Toronto, Ontario Canada, 4Work & Mental health Research Unit, Institute of Mental Health Research, University of Ottawa, Ottawa, Ontario Canada, 5School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Ontario Canada, 6Department of Psychiatry, University Health Network, Toronto, Ontario Canada, 7Department of Psychiatry, St. Michael’s Hospital, Toronto, Ontario Canada, 8Arthur Sommer Rotenberg Chair in Suicide and Depression Studies, St. Michael’s Hospital, Toronto, Ontario Canada, 9Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Ontario Canada, 10Krembil Research Institute, University Health Network, Toronto, Ontario Canada, 11Department of Radiology, University of Calgary, Calgary, Alberta Canada, 12Alberta Children’s Hospital Research Institute, Calgary, Alberta Canada; 13 Child & Adolescent Imaging Research (CAIR) Program, Calgary, Alberta Canada
Family flexibility and cohesion are at times impaired in families of first-episode psychosis patients compared to healthy controls (HCs). Furthermore, family functioning may be important even before the onset of illness. A positive family environment may be related to a decrease in symptoms and improved functioning in youth at clinical high-risk for psychosis. However, little is known about earlier stages of risk and the importance of the family environment for youth at-risk for serious mental illness (SMI).In the PROCAN study, we examined family functioning from the Circumplex Model of Family Systems in a large sample of youth at-risk for SMI. Family functioning was evaluated with the Family Adaptability and Cohesion Evaluation Scales-IV (FACES-IV) for 41 youth with a family history of SMI (Stage 0), 52 distressed youth with early mood and anxiety symptoms (Stage 1a), 105 youth with subthreshold psychotic symptoms (Stage 1b), and 42 HCs. Results from multivariate linear regression analyses showed that participants in Stage 1a and Stage 1b significantly differ from HCs in all the family functioning scales. Furthermore, participants in Stage 0 differed from participants in Stage 1b; and similarly, participants in Stage 1a differed in all the scales from participants in Stage 0. Therefore, family functioning appears to be decreased in youth at-risk for SMI who present with early signs of mood, anxiety or subthreshold psychotic symptoms.
Topic Area: Ultra High Risk / Prodromal Research