Symposia

Guidelines

Important information

IEPA 12 CANCELLED

  • Each symposium must be submitted under one subject to ensure cohesive presentations
  • Time slot will be 1 hour 30 mins
  • Each symposium will have a chair, a co-chair is optional (Chairs can be presenters)
  • Maximum number of presenters is 4 with each presentation being approximately 15 mins with 5 mins for discussion
  • A symposium overview (1,700 characters including spaces) has to be submitted alongside the abstracts of the individual symposium presentations.
  • All abstracts are limited to 1,700 characters (including spaces)
  • Abstracts must be new and may not have been previously presented.
  • Titles are limited to 150 characters (including spaces)
  • All abstracts must be submitted and presented in English.
  • Presentation abstracts must be divided into the following topics: aims, methods, results and conclusions.
  • All speakers are required to register for the meeting by 1st June  2020 in order to have the symposium included in the final program and listed in the Abstract Book.

Detailed Information

  • Symposia should deal with early intervention topics in mental health and reflect the overarching theme of the conference: ‘New Frontiers in Early Intervention’.
  • Symposia can be organized along the lines of content or methodology in the primary and secondary themes provided. Individual abstracts should include the aims, methods, results and conclusions for each topic.
  • The presenting author is required to ensure that all co-authors are aware of the content of the abstract before submission.
  • Submitted abstracts should include non-published data. Abstracts previously presented will not be accepted.
  • Figures and graphics will not be accepted at this point, so you must include only the abstract itself.
  • Your abstract is not successfully submitted until you receive a confirmation e-mail after clicking the final submit button. If you do not receive a confirmation e-mail, please check your spam mailbox and contact us.
  • Submission of the abstract constitutes the consent of all authors to publication (e.g. Conference website, programs, other promotions, etc.)
  • All communications will be sent to the email used to submit the abstract.
  • All abstracts must be submitted via the on-line system. Abstracts sent by email WILL NOT be accepted.

List of themes

Overarching Theme: New Frontiers in Early Intervention

Primary Themes:

  • Basic Neuroscience
  • Diagnosis and Phenomenology
  • Electrophysiology
  • Epidemiology
  • Ethical Issues
  • Genetics
  • Neurocognition
  • Neuroimaging
  • Psychopharmacology
  • Psychosocial Interventions
  • Public Policy
  • Service System Development and Reform
  • Stress Responsivity
  • Substance Use
  • Translational Research

Secondary Themes:

  • Anxiety Disorders
  • Comorbid Conditions
  • Eating Disorders
  • First Episode Psychosis
  • Mood Disorders
  • Neurodevelopmental Disorders
  • Personality Disorders
  • Psychosis NOS
  • PTSD (Post Traumatic Stress Disorders
  • Transdiagnostic Approaches
  • Trauma
  • Ultra High Risk/Prodromal Research
  • Other

Submission Instructions

  • All submissions must be written in English and in final form and ready for publication in the Abstract Book.
  • Your submission will NOT be reviewed for typos or other errors.
  • Check your work carefully as no changes will be allowed after the submission deadline.
  • Title
    • Do not enter the title in all capital or all lowercase letters.
      Title case is the preferred format.
  • Abstract
    • The abstract must be a single paragraph not exceeding 1,700 characters.
    • Multiple paragraphs will be merged into a single paragraph.
    • Line breaks, tabs and multiple spaces will be replaced with single space.
    • Formatting, such as italic and bold, is not supported.
    • Abstracts must be new and may not have been previously presented.
  • Authors
    • The first author will be listed in the published program as the speaker.
    • Middle name or initials should be entered in the First Name field.
    • Do not enter names in all capital or all lowercase letters.
    • For affiliation numbers, enter the appropriate number, or numbers, next to each speaker to indicate which schools or universities the author is affiliated with.
    • When entering affiliation numbers, use the format 1,2,3 with no spaces.
  • Affiliations
    • Enter each school or university name only once, then associate affiliations with a speaker using the Affiliation numbers box.
    • Do not enter addresses or department names; they will be removed.
    • Do not enter affiliations in all capital or all lowercase letters.
    • Authors and affiliations will be published in this format:
      Joe Smith1, Jane Jones1,2; 1Stanford University, 2UCLA

Presentation Format

  • The recommended format for presentation is an introduction of the symposium by the chair, followed by four individual presentations with Q&A. Discussion time can be scheduled according to the organizers’ discretion (e.g., after individual presentations, concentrated at the end of a session, or a mixture of the two approaches.
  • Symposia sessions are 90 minutes. Symposia benefit from a diversity of perspectives and institutional affiliations. Proposals from young investigators are encouraged.
  • The symposium organizer is listed as the chair of the symposium; additional co-chair and/or discussant is considered optional. All speakers are required to register for the meeting by 1st June 2020 in order to have the symposium listed in the printed program.

Multiple Submissions

  • Submitting a symposium proposal and/or speaking in a symposium does not prevent you from submitting an abstract for an oral presentation or poster presentation, however IEPA will not allow any encore presentations at the meeting. Chairpersons must ensure that all speakers are committed to participating in the symposium before submitting a proposal. If a symposium presentation has more than one author, it should be presented by the first author.

Abstract Review Process

  • Proposals will be evaluated by the IEPA 12 Scientific Committee using a variety of criteria including scientific merit, timeliness, theoretical innovation and breadth, methodological innovation, lack of overlap with the regular program, and diversity of the speakers.
  • Individual authors whose abstract was not accepted as part of a symposium session may re-submit their abstract as an oral or poster presentation. The last day to submit symposia abstracts for presentation at the meeting is 14th February 2020.

Contact Info

E-mail: abstractbrasil@mci-group.com
T: +55 (21) 3174-4609
C: +55 (21) 97234-8372

The Next Stage for Early Intervention:
Transdiagnostic, Personalized, Universal

australia

Professor Patrick McGorry

University of Melbourne

Early intervention in mental health has made great progress over the past 25 years through the prototype of early psychosis. Yet real world reform remains relatively piecemeal and comprehensive upscaling has not yet occurred to enable every person with psychotic illness is to receive timely, personalised and sustained clinical care and reach their full potential. Nevertheless, the beachhead and evidence base established by the EI paradigm in psychosis creates the conditions for this principle to be extended to the full diagnostic spectrum.

EI has universal value in health care and the fluidity of our syndromal approach to diagnosis both cross-sectionally and longitudinally means that we cannot focus too narrowly. The clinical staging model may provide the framework for us to translate the principles of early intervention to a wide range of mental disorders. New cultures of care appropriate to early intervention are needed and emerging. Through more refined prediction strategies and definition of underlying mechanisms we can also move towards the holy grail of a more personalized approach to treatment.

Transdiagnostic research can be enabled if systems of care guarantee “soft entry” to new cultures youth-oriented culture of care, at the sub threshold stage, making stepwise expertise progressively available with functional recovery as the goal.

We need to combine the power of the evidence-based paradigm with greater confidence, tenacity and much more intensive and professional advocacy in partnership with the general public.

Tales from the frontline:
understanding the impact of psychosis on families

uk

Dr Juliana Onwumere

King’s College London

To provide optimal patient care, all health systems, including mental healthcare, need families. They rely on their support, expertise, and the ‘safety net’ they all too often provide.  To what degree, however, do these health systems understand the different ways in which families can be directly and indirectly impacted by their support and caregiving roles? To what extent do health and social care providers consider the information, support, and health needs of families, and how these might vary depending on different illness phases, family configurations, and socio-economic factors.  

This talk will seek to shine a spotlight on the families of people with lived experience of psychosis. It will explore how our current understanding of families, and the specific health needs of carers, have evolved over recent decades and what evidence gaps remain. The implications for family caregiving, service provision and policy will be discussed

Immune system as a potential target for treatment and prevention of serious mental illness and comorbid cardiometabolic diseases

uk

Dr Golam Khandaker

University of Cambridge

The immune system, particularly low-grade systemic inflammation, has been implicated in pathogenesis of depression and schizophrenia. Inflammation is thought to be a clinically relevant phenotype, as immune activation is associated with poor response to psychotropic medications.

Currently, a number of RCTs are testing the efficacy of novel anti-inflammatory drugs for patients with depression and schizophrenia. However, there are key unanswered questions both mechanistic and clinical. Is inflammation a causal risk factor for depression and schizophrenia? Could anti-inflammatory treatment be used to treat these disorders? If so, which patients are likely to benefit? 

Dr Khandaker will present evidence from population-based longitudinal studies and Mendelian randomization genetic analysis addressing the issue of causality. These studies suggest that reverse causality or residual confounding is unlikely to fully explain the associations of interleukin 6 (IL-6), a pro-inflammatory cytokine, with depression and schizophrenia. He will present data from systematic reviews and meta-analysis on the effect of anti-inflammatory drugs, including monoclonal antibodies, on depressive symptoms.

These studies have led to two proof-of-concept double blind RCTs of tocilizumab (anti-IL-6R monoclonal antibody) for patients with depression and first episode of psychosis including the ongoing Insight study (ISRCTN16942542), which will be discussed.

Furthermore, Dr Khandaker will present emerging evidence from genetic and epidemiological analysis suggesting that inflammation be a shared mechanism for comorbid cardiometabolic disease in people with serious mental illness.

Widening the clinical and geographical frontiers of
neurodevelopment studies - the Brazilian High Risk Cohort Study

brazil

Professor Rodrigo A Bressan

Federal University of Sao Paulo

Most psychiatric disorders emerge during adolescence preceded by a phase during which attenuated symptoms and functional decline become apparent. The clinical presentation and course of the mental disorders is extremely variable and poorly understood.

Neurodevelopment cohort studies are beginning to provide new insights about the interaction between neurobiological and environmental processes during this period. However, there is still an enormous gap in knowledge that is even more pronounce in Low and Middle Incomes Countries (LaMIC), where almost 90% of the world’s youth live. Research outputs from a large cohort study, the “Brazilian High Risk Cohort Study” (BHRCS) (https://osf.io/ktz5h/ ) that combines epidemiology and neuroscience methods to follow 2,511 6-12 years-old Brazilian children for up to 10 years now will be presented.

Altered neurodevelopmental trajectories were associated with incident mental disorders using neuroimaging, genetics, cognition, and in-depth psychiatric evaluations. Analyses of baseline and 3-year follow-up data have already added to previous literature. A large treatment gap in Brazil (only 1 in 5 children with a mental disorder had received any lifetime mental health care).

Research finding about reduced fractional anisotropy of the superior longitudinal fasciculus in children with poor decoding and writing skills; increased centrality of cortical brain networks during the transition to adolescence. Aberrant intrinsic connectivity within the reward network linked with new-onset adolescent depression. Early findings on high-risk stratification, and COVID mental-health impacts from the last wave of data collection (18-21 years-old) will be presented.

Prevention and Early Intervention in Low and Middle-Income Countries: from Neuroscience to Public Health

brazil

Giovanni Salum

Universidade Federal do Rio Grande do Sul – Brazil

In this presentation, I will discuss strategies for health prevention, promotion, and treatment in low and middle-income countries. I will discuss original data on strategies from neuroscience and pragmatic implementation strategies in low resource settings.

Intergenerational Psychiatry: A New Look at a Powerful Perspective

usa

Cristiane S. Duarte

Columbia University – USA

The talk will start by discussing recent developments in our understanding of intergenerational processes in psychiatry, from animal studies to converging evidence among humans, expanded by new tools now available, such as neonatal brain imaging, and others (Duarte, Monk, Weissman & Posner, World Psychiatry, accepted).

Specific mechanisms and the potential of an intergenerational approach for broadening our understanding of developmental processes in Psychiatry will be illustrated by ongoing studies of individuals growing up in disadvantaged contexts, particularly, the Boricua Youth Study and the Brazil Babies Study.

Preventing the onset of depressive disorders:
Opportunities and challenges

netherlands

Pim Cuijpers

University of Amsterdam – Netherlands

Depression is common, costly, has a strong impact on the lives of individuals and society and has a strong association with morbidity and mortality. Preventing the onset of depressive disorders is one of the main challenges for public health in the coming decades. In this presentation an overview of the research field will be given. Why prevention is important, whether preventive interventions are effective, examples of important trials in the field will be given, and possibilities to increase the impact on public health will be discussed.

Youth mental health in troubled times

hongkong

Eric Chen

University of Hong Kong – Hong Kong

Youth mental health (YMH) initiatives are vital to reducing the overall impact of mental disorders in a population. A large-scale community YMH program was due to launch when social unrest broke out in Hong Kong in 2019, which saw huge increases in mental distress in the population. The subsequent emergence of COVID-19 superimposed a further layer of stressors and difficulties.

Engagement with services was hampered by a lack of trust and polarization in society. Evaluation of mental health was complicated by the persistence of population-level stressors. Data from an innovative large-scale survey and conventional epidemiological approaches complement one another to provide a more comprehensive picture of the extent of the mental health sequelae, as well as their underlying triggers.

We observed that compared to the rest of the population, young people were particularly affected. Exposure to pandemic-related and unrest-related factors interacted in complex ways to aggravate PTSD and depressive symptoms. Given the increasing co-occurrences of pandemic and social protests, these observations may be relevant to understand how population-level stressors impact on youth mental health in other communities.

Early intervention for developing positive social relationships:
Can we prevent bullying victimization and loneliness

uk

Louise Arseneault

King’s College London – UK

Social relationships and interpersonal connections are fundamental to human life. Positive social relationships provide support in times of stress, while the absence or removal of these connections causes distress and presents potential long-term implications health and functional outcomes. Research reported poor mental, physical and functional outcomes associated with being bullied in childhood and with loneliness in young adulthood. Interventions aiming to reduce these phenomena are numerous but with limited results.  

This presentation will examine evidence supporting early intervention to prevent bullying victimization in childhood and loneliness in your adulthood. 

The North American Prodrome Longitudinal Study:
NAPLS 1-3 the development of a consortium

canada

Jean Addington

University of Calgary – Canada

The North American Prodrome Longitudinal Study (NAPLS) consortium was initiated in 2003 with eight independently National Institute of Mental Health (NIMH) funded sites. Sites included the Universities of Yale, Calgary, North Carolina, Emory, Harvard, and the University of California at San Diego and at Los Angeles.

In 2008, they were awarded a 5-year grant from NIMH to incorporate biological assessment approaches (neuroimaging, electrophysiological, hormonal and genetic) into a multi-site prospective study of 720 participants at clinical high risk for developing psychosis and 240 matched controls, known as NAPLS 2. Then in 2014 NAPLS was competitively renewed for a new 5-year study period (NAPLS 3) to further clarify the roles of neuroinflammation and deficient synaptic plasticity in the development of psychosis and a 9th site, the University of California, San Francisco was added.

Numerous papers have been published from the NAPLS project, an overview of which will be part of the focus of this presentation. The next step for this collaboration is to work with other consortiums with the aim of moving the field to newer levels.

Reflections around the prevention of depression

uk

Ricardo Araya

King’s College London – UK

Despite some interesting ideas and results, the prevention of emotional disorders remains an elusive concept with limited evidence to guide further developments. The limited knowledge on the aetiology of emotional disorders limits our capacity to develop better interventions. 

This presentation will address some issues such as time sensitive periods to act, types of prevention intervention, and methodological and practical challenges based ons tudies conducted mostly inlow-and-middle-income counrtries.