A longitudinal cohort study of mortality in First Episode Psychosis

Poster A77, Thursday, October 20, 11:30 am - 1:00 pm, Le Baron

Roisin Doyle1, Donal O'Keeffe1,2, Ailish Hannigan3, Anthony Kinsella4, Kevin Madigan5, Elizabeth Lawlor1, Ann Sheridan6, Aine Kelly7, Mary Clarke1,8; 1Dublin and East Treatment and Early Care Team (DETECT) Services, Blackrock, Co. Dublin, Ireland, 2School of Nursing and Midwifery, Trinity College Dublin, Dublin 2, Ireland, 3Graduate Entry Medical School, University of Limerick, Limerick, Ireland, 4Molecular and Cellular Therapeutics Department, Royal College of Surgeons in Ireland, Dublin, Ireland, 5Saint John of God Community Mental Health Services Limited, Co. Dublin, Ireland, 6School of Nursing Midwifery and Health Systems, University College Dublin, Belfield, Dublin 4, Ireland, 7Research Department, Saint John of God Hospitaller Ministries, Stillorgan, Co. Dublin, Ireland, 8School of Medicine and Medical Science, University College Dublin, Belfield, Dublin 4, Ireland

Purpose: Increased mortality rates have been found in those with a diagnosis of psychosis; studies suggest a shortened life expectancy of 15-20 years less than that of the general population. This study aimed to calculate the mortality rate of this cohort, compare it to that of the general Irish population, and examine the clinical and social factors that may impact on increased risk of premature death in psychosis. Materials and Methods: 171 individuals diagnosed with a first episode psychosis identified between 1995 and 1999 in a community mental health service were traced. Mortality was established by matching death certificates to deceased cohort members (using name, age at date of death, and address at date of death). Date of first presentation to service was used as date of entry point and date of death or end of follow up as the end point. Results: 12.28% of cohort members (n=20/171) were recorded as deceased. Older age at point of entry to the study was the only variable associated with an increased risk of all-cause mortality. 9 deaths were attributed to natural causes; 7 to unnatural causes; and 4 were unknown. Conclusion: Findings suggest that the mortality gap in people with schizophrenia and other psychoses remains high. Early intervention services should consider physical health interventions to address this.

Topic Area: First Episode Psychosis

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